Who should avoid certain altered states?

Short Answer

Individuals with psychotic disorders, severe depression, heart conditions, seizure disorders, or those taking certain medications should avoid most psychedelic and dissociative altered states.

Why This Matters

Altered states can trigger latent psychiatric conditions because they temporarily disrupt normal brain function and neurotransmitter balance. Psychedelics particularly affect serotonin systems, which can worsen mood disorders or precipitate psychotic episodes in vulnerable individuals. Cardiovascular risks emerge because many consciousness-altering substances increase heart rate and blood pressure. Drug interactions occur because altered state inducers often affect the same liver enzymes that metabolize prescription medications.

Where This Changes

Risk levels vary significantly based on the specific altered state method, individual medical history, and supervision quality. Some meditative or breathwork-induced states may be safer alternatives under proper guidance, while certain prescription medications can be safely paused temporarily with medical oversight.