Agmatine users: has it remained its efficiency?

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I’m looking for something that helps with depression and anxiety and I hear great things, as well as its tolerance reducing benefits. My question is, does it continue to work after continued dosing or does it fade out? I’ve used a few different noots/supps that worked excellent from days to weeks and then just stopped and I’m wondering if anyone has had that with agmatine? Does it work immediately or do the benefits seem to come after it wears off/next day?

Also, any experiences with it (positive or negative) would be really appreciated especially regarding anxiety and depression.

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